Drug discovery case study pdf

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Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from actual examples. Each case study focuses on a particular drug and therapeutic target, guiding readers through the drug discovery and development process, including drug design rationale, structure-activity relationships, pharmacology, drug metabolism, biology, and clinical studies. Case Studies in Modern Drug Discovery and Development begins with an introductory chapter that puts into perspective the underlying issues facing the pharmaceutical industry and provides insight into future research opportunities. Next, there are fourteen detailed case studies, examining:. Drugs designed for different therapeutic areas such as cardiovascular disease, infection, inflammation, cancer, metabolic syndrome, and allergies.
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Open Innovation Case Study: GSK’S Centres of Excellence for External Drug Discovery

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Medicinal Chemistry: The Modern Drug Discovery Process by Erland Stevens | Pearson

Emphasizing applications of chemistry while reinforcing theory—especially in the areas of organic and physical chemistry—this new text prepares students for career success in the pharmaceutical, medical, and biotech industries. Medicinal Chemistry: The Modern Drug Discovery Process delivers a comprehensive introduction to medicinal chemistry at an appropriate level of detail for a diverse range of undergraduate students pharmaceutical, chemical engineering, premed, biotechnology. Case Studies in each chapter demonstrate real life applications of newly introduced ideas. Click on the link below to view the chapter in PDF.
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Case Studies in Modern Drug Discovery and Development

The Drug Discovery Series covers all aspects of drug discovery and medicinal chemistry and contains over seventy books published since Providing comprehensive coverage of this important and far-reaching area, the books encourage learning in a range of different topics and provide valuable reference sources for scientists working outside their own areas of expertise. Books feature case studies to bring different aspects of the drug discovery process alive and they detail the fundamental science necessary for understanding through to the most up-to-date discoveries and cutting-edge technologies. Chapters are written and edited by experienced researchers from both industry and academia.
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Accounts in Drug Discovery describes recent case studies in medicinal chemistry with a particular emphasis on how the inevitable problems that arise during any project can be surmounted or overcome. The Editors cover a wide range of therapeutic areas and medicinal chemistry strategies, including lead optimization starting from high throughput screening "hits" as well as rational, structure-based design. The chapters include "follow-ons" and "next generation" compounds that aim to improve upon first generation agents.
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